“The acquisition of TxCell immediately positions Sangamo as the leader in CAR-Treg development,” said Sandy Macrae, CEO of Sangamo. “We’re thrilled to work with our colleagues in France toward an exciting new future together developing CAR-Tregs. By combining Sangamo’s zinc finger nuclease gene editing technology with TxCell’s CAR-Treg platform, we have the potential to develop a pipeline of novel cell therapies for patients suffering from autoimmune and inflammatory disorders.”
In 2019, Sangamo expects to submit a clinical trial authorization application (CTA) in Europe for TxCell’s first CAR-Treg investigational product candidate for solid organ transplant.
