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VARIOUS DRUG INTERACTIONS AND THEIR RELATIVE EFFECT | GPAT DISCUSSION CENTER
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VARIOUS DRUG INTERACTIONS AND THEIR RELATIVE EFFECT
- March 5, 2018
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- Aluminium Hydroxide Gel + Pseudoephedrine = Decrease effect of that drug due to increases pH of gastric fluid
- Ciprofloxacin + Theophyline = Increases plasma level of Theophyline
- Aminoglycoside + beta-Lactam antibiotics= Synergestic effect but if given in same syring it‘s become inactive due to complex formation
- Cortisone + Ampicillin= Antagonist
- Erythromycin /Clarithromycin/ Telrithromycin + Carmazepam/ Phenytoin = Increases level of Carbamazapine and Phenytoin
- Methotrexate + Sulfamethoxazole = Displace from binding site and increases free plasma concentration of drug
- Amphotericin B + Flucytosine = Synergestic effect
- Ketoconazole + Amphotericin B = Antagonized effect due to decreases ergosterol level
- Azoles ( including All) + Terbinafine = Contraindicated
- Posconazole + Ergot alkaloid = Contraindicate
- Cimetidine + Terbinafine= increases plasma concentration of Terbinafine
- Gresiofulvin + Alcohol = Potentiate toxicity of alcohol
- Miconazole+ Warfarin = inhibit metabolism of warfarin
- MAO inhibitors + Pethidine = Hyperpyrexia
- TCA + SSRIs TCA = toxicity
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